A Holstein-Lewis fracture is specifically associated with a high risk of injury to the radial nerve. This fracture pattern is defined as a:

Explanation:
A Holstein-Lewis fracture is a spiral fracture of the distal third of the humeral shaft. It carries a particularly high risk of radial nerve palsy (up to 22%) because the nerve becomes tethered as it passes through the lateral intermuscular septum in this region, making it highly susceptible to laceration or entrapment by the mobile distal fracture fragment. Reference: Rockwood and Green's Fractures in Adults, 9th Edition.