According to the American Academy of Orthopaedic Surgeons (AAOS) Clinical Practice Guidelines, what is the standard, strongly recommended prophylactic systemic antibiotic regimen for a routine primary total joint arthroplasty in a patient with no reported medication allergies?

According to the American Academy of Orthopaedic Surgeons (AAOS) Clinical Practice Guidelines, what is the standard, strongly recommended prophylactic systemic antibiotic regimen for a routine primary total joint arthroplasty in a patient with no reported medication allergies?

A Intravenous Cefazolin administered completely within one hour prior to the surgical incision.
B A combination of intravenous Vancomycin and oral Rifampin administered two hours prior.
C A continuous 24-hour preoperative infusion of intravenous Clindamycin.
D Oral Cephalexin prescribed for 3 days preoperatively, followed by IV Penicillin intraoperatively.
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