TOPIC: RANDOM MIX
A 65-year-old female presents with a low-energy distal radius fracture. Her DEXA scan reveals a T-score of -2.6 at the femoral neck. According to WHO criteria, what is her diagnosis, and what is the primary mechanism of action of the first-line pharmacological treatment?
A
Osteopenia; RANKL inhibition via monoclonal antibodies
B
Osteoporosis; stimulation of osteoblast-mediated bone formation via PTH analogues
C
Severe osteoporosis; inhibition of osteoclast-mediated bone resorption via bisphosphonates
D
Osteomalacia; enhanced calcium absorption via Vitamin D supplementation